Figure 6

Induction of NFκB signaling after particle treatment. NR8383 cells were treated with particles as indicated in concentrations of 40 μg/cm2 for 1 h. Compared to (A) untreated AM, (B) DQ12-treated cells show the strongest nuclear staining, while (C) fTiO2 and (D) ufTiO2 particles demonstrate a lower nuclear staining. Original magnification: 400-fold (Zeiss Axio Observer.D1).