Figure 9

(Upper layer) CLSM pictures of NR8383 and Caco-2 cells after 24 h exposure to a non-toxic concentration of 1 μg/ml of different PNP ₉₀ (λ _ex  = 488 nm and λ _em  = 543 nm) with phase contrast figures given as inserts. (Lower layer) Relative cellular uptake of different PNP₄₅[4] and PNP₉₀ in NR8383 and Caco-2 cells after 24 h exposure with the PNP₄₅-NH₂ (1 μg/ml) values taken as 100 % (n = 5). The * sign signifies p < 0.05 when compared to the data for PNP₄₅-NH₂. The “†” sign signifies p < 0.05 when compared between the PNP₄₅ and PNP₉₀.