Fig. 11

Effects of WSPM, LaCl3, CeCl3, NdCl3 and NaF on the A549 cell cycle regulator protein expression. A549 cells were treated with WSPM2.5 (100 µg/ml or 200 µg/ml) or WSPM10 (100 µg/ml or 200 µg/ml) or NaF (2 mM or 5 mM) or CeCl3 (1 mM or 2 mM) or LaCl3 (1 mM or 2 mM) for 24 h. Cell lysates were immunoblotted with the indicated antibodies. A549 cells treated with either DMSO or 5 nM actinomycin D were used as negative control (NC) and positive control, respectively. Each experiment was repeated three times independently. *Compared wih the NC group, P < 0.05; **Compared with the NC group, P < 0.01