Fig. 1

Experiment Design Timeline. Mice were fed a healthy or high-fat western diet for 14 weeks and exposed to either water (control) or AgNPs (50 µg) via oropharyngeal aspiration. 24 h post-exposure, mice were treated with saline (control) or RvD1 (400 ng) via oropharyngeal aspiration. Endpoints associated with inflammation and lipid metabolism were examined at 3-, 7-, 14-, and 21-days following AgNP exposure