Fig. 11
Total dissolution (includes all lung regions and the gastrointestinal tract) available for absorption into blood. Mn-laden aerosol (concentration = 100 µg-Mn/m3) of indicated sized particles (density = 5.08 g/cm3) were inhaled while a light exercise level of activity for 8-h/day, 5 day/week, for 3 years by adult male exposed by during ferroalloy work (MMAD = 2.6 µm) and battery manufacturing (MMAD = 5 µm). The 5 days/week exposure was implemented by reducing the daily amount of air inhaled by 5/7 to smooth the illustrated lines. The Mn form that workers were exposed to was assumed to be MnO2, the MnSO4 line illustrates the daily dissolution rate of a highly soluble Mn form. The daily dissolution includes gastrointestinal absorption of 5% for MnSO4 and 0.05% for MnO2