Fig. 9

Total dissolution (includes all lung regions and the gastrointestinal tract) of particles normalized to amount of material inhaled. Monodisperse aerosol (concentration = 1.0 µg/m3) of indicated sized particles (density = 3 g/cm3) were inhaled for 8-h/day for 3 years by adult male exposed while sitting at rest. The daily dissolution reflects that occurring on day 1095 of exposure with gastrointestinal absorption of 10%