Fig. 3

SiNPs induced iron overload and lipid peroxidation in rat hearts. Total iron and Fe²⁺ contents in rat serum (A) and heart tissues (B). n = 4. C Protein expressions in rat heart tissues. n = 3. D GSH content in serum. E Immunofluorescence of ROS (a) and corresponding fluorescence intensity analysis (b). n = 4. Scale bar, 100 μm. F MDA content in rat hearts. n = 4. G Correlation analysis of the indicators in rats. n = 4. Data were expressed as mean ± SD. ^*p < 0.05 vs control