Fig. 6

Fer-1 alleviated SiNPs-elicited ferroptosis in cardiomyocytes. A Cell viability, B LDH activity, C GSH, and D MDA contents were measured in AC16 cells after Fer-1 and SiNPs treatment. E Through C11-BODIPY581/591 labeling, the cellular level of lipid ROS was quantified by FCM. F Western blot analysis. Data were expressed as mean ± SD. *p < 0.05 vs control, #p < 0.05 vs SiNPs