Fig. 4
From: Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles
Transepidermal penetration of NPs. The epidermal structure of human skin (a) was simulated by the 3D keratinocyte culture (b) which showed well-stratified keratinocytes as seen in real human skin (c). The depth of NPs in the epidermis and densities of NPs at the basal layers of the epidermis at 4 h post-treatment (hpt; left) and 16 hpt (right) were visualized by in-depth 3D scanning of the culture constructs (d). Scale bar: 50 μm