Fig. 2

Titanium concentrations in lung compartments. These were assessed 18 h, 7 days and 14 days after a single (1 day) TiO2 exposure. Or at 18 h, 30 days or 60 days after a repeated (2 × 5 days) TiO2 exposure in control animals and low, mid and high exposure groups (n = 4 per group) in (A) lavage lung tissue after a single exposure, (B) lavage lung tissue after a repeated exposure, (C) BAL fluid after a single exposure (D) BAL fluid after a repeated exposure, (E) BAL cells after a single exposure and (F) BAL cells after a repeated exposure. Titanium concentrations in lavage lung tissue are expressed as µg/g of dry weight, and in BAL fluid and BAL cells as µg/g of wet weight