Biodistribution of cerium dioxide and titanium dioxide nanomaterials in rats after single and repeated inhalation exposures

Table 1 Aerosol parameters of CeO₂ NM-212

Nominal particle size (nm)	28.4 ± 10.4
Estimated effective density (g/cm³)	1.5–2.4
Exposure schedule	1 day*			2 × 5 days#
Target concentration (mg/m³)	20			5
Gravimetric concentration (mg/m³) ± sd	20.9	±	1.60	5.07	±	0.12
Particle number concentration (p/cc) ± sd	5.5E + 05	±	1.10E + 05	7.1E + 04	±	6.3E + 03
MMAD (µm) ± GSD	1.05	±	1.66	1.09	±	1.76
CMD (nm) ± gsd	152	±	1.85	154	±	1.86

* relative humidity of the test atmosphere was 46.2–61.4%RH and the temperature was 22.3–24.2 °C
# relative humidity of the test atmosphere was 47.3–60.7%RH and temperature was 22.1–24.4 °C

ISSN: 1743-8977