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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Effects of simulated smoke condensate generated from combustion of selected military burn pit contents on human airway epithelial cells

Fig. 2

Flaming condensate modulated DEGs and pathways. DEGs from flaming condensate exposure groups were further analyzed to identify the most potent source material and commonality in gene expression modulation. Euler plot (a) showing plywood flaming condensate resulted in the most DEGs compared to cardboard and plastic. (b) Heatmap of the 47 common DEGs from all flaming condensates showing relative levels for each condensate obtained by adding the RNA-seq count values and scaling for each gene: 18 and 29 genes being respectively down- and up-resulted by all flaming condensates. Pathway analysis (c) of the 47 common DEGS exhibited impact on immune cell migration and detoxification. The color of the scale in panel B denotes relative expression level of each gene across the four groups. Scale in panel C denotes adjusted p-value

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