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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants

Fig. 2

DE induced extensive gene dysregulation. (A) Heatmap of all differentially expressed genes (DEGs) using FA as reference group. (B) Gene set enrichment analysis (GSEA) of DE and DE + FA shows dissimilar patterns of gene expression. Top panel shows the gene expression pattern and heatmap for genes involved in respiratory electron transport, and ATP synthesis in the DE group. Bottom panel shows the gene expression pattern and heatmap for genes involved in PPARα activates gene expression gene set in the DE + FA group

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Particle and Fibre Toxicology

ISSN: 1743-8977

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