Fig. 1
From: Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis
Visualization of a representative MeONP, La2O3, in mouse lungs
(A) TEM imaging of MeONPs in lung tissues. Mice exposed to La2O3 were sacrificed at 24 h, and lung tissue sections were prepared for TEM observations. Arrows, A, V, and L indicate MeONP, alveoli, vessels, and lysosomes, respectively, in TEM images. (B) Confocal imaging of MeONPs in cells. THP-1 cells exposed to 50 µg/mL FITC-labeled MeONPs were fixed and stained with Hoechst 33,342 (blue), WGA conjugated with Alexa Fluor 594 (red), or LysoTracker DND-99DAPI (red) for confocal imaging