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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis

Fig. 6

Contributions of descriptors in predicting MeONP-induced lung fibrosis

RF classification analysis was performed to quantify the contributions of eighteen descriptors to MeONP-induced lung fibrosis. Seven descriptors, namely IL-1β release in macrophages, NADH levels in macrophages, TGF-β1 release in epithelial cells, dissolution in PSF, zeta potential, hydrodynamic size, and NADH levels in epithelial cells, were identified as pivotal features determining MeONP-induced lung fibrosis

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