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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon black

Fig. 5

Relationship between the proposed rat adverse outcome pathway. [9] and genes modulated by particle overload in rat AM. The large rectangles represent the different proposed key events linked to high exposure to PSLT particles in rats, leading to lung adverse outcomes. The grey small rectangles represent the genes significantly modulated by P25 and Printex 90 particle overload in rat AM

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